Hematological Changes in Opium Addicted Diabetic Rats

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Hematological Changes in Opium Addicted Diabetic Rats

BACKGROUND Chronic opioid treatment in animal models has shown to alter hematological parameters. OBJECTIVES The aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (RBCs) indices in diabetic rats. MATERIALS AND METHODS Peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and ...

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hematological changes in opium addicted diabetic rats

objectives the aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (rbcs) indices in diabetic rats. materials and methods peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and normal male and female rats and hematological parameters were measured. results the mean number of whi...

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Ovary Cells Apoptosis in Opium-Addicted Diabetic and Non-Diabetic Rats

BACKGROUND Apoptosis is a physiological mechanism of cell death and it can be triggered by a variety of internal and external stimuli. It has been indicated that some opium derivatives develop cell apoptosis. OBJECTIVES The aim of this investigation was to evaluate the effect of opium addiction on ovary cell apoptosis in diabetic and non-diabetic Wistar rats. MATERIALS AND METHODS This expe...

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Impact of Opium on the Serum Levels of TGF-β in Diabetic, Addicted and Addicted-Diabetic Rats

Background: Several cells of immune system such as regulatory T cells and macrophages secrete transforming growth factor-β (TGF-β) in response to different stimuli. This cytokine has inhibitory effect on immune system and diminished production of this cytokine is associated with autoimmune disorders. Objective: The aim of this study was to evaluate the influence of opium addiction on serum leve...

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impact of opium on the serum levels of tgf-β in diabetic, addicted and addicted-diabetic rats

background: several cells of immune system such as regulatory t cells and macrophages secrete transforming growth factor-β (tgf-β) in response to different stimuli. this cytokine has inhibitory effect on immune system and diminished production of this cytokine is associated with autoimmune disorders. objective: the aim of this study was to evaluate the influence of opium addiction on serum leve...

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ژورنال

عنوان ژورنال: International Journal of High Risk Behaviors and Addiction

سال: 2013

ISSN: 2251-8711,2251-872X

DOI: 10.5812/ijhrba.8777